Fundamentals of Medical Imaging, 3rd edition

Fundamentals of Medical Imaging, 3rd edition
3D rendered view of structural and functional imaging of the brain of a patient with an arteriovenous malformation (AVM) in the right semioval center. Anatomical high-resolution T1-weighted MR images show the brain anatomy and skull surface. Arteries were rendered in red from time-of-flight (TOF) MR angiography (MRA). The corticospinal tract (CST, in yellow) and the superior longitudinal fascicle (SLF, in blue) were obtained by tractography in diffusion MR images. Functional MRI data from a verb-to-noun generation language task were rendered as purple blobs and the green sensorimotor blobs were obtained using a finger-clenching task versus rest. The nidus of the AVM can be seen in the semioval part of the CST where its fibers are displaced by the vessels. This comprehensive integrated 3D view enables risk assessment prior to treatment of the AVM. (Courtesy of Professor S. Sunaert, Department of Radiology, University Hospitals Leuven.)

This book explains the applied mathematical and physical principles of medical
imaging and image computing. It gives a complete survey of how medical images
are obtained and how they can be used for diagnosis, therapy, and surgery. It is accompanied by about 400 color illustrations and 80 video clips.

It has been written principally as a course text on medical imaging intended for graduate and final-year undergraduate students with a background in physics, mathematics, or engineering. However, an effort has been made to make it readable for biomedical scientists and medical practitioners by avoiding unnecessary maths, without giving up the depth needed for physicists and engineers. Mathematical proofs and details are highlighted in separate paragraphs and can be skipped without hampering a fluent reading of the text.
Medical imaging and image computing are rapidly evolving fields and this edition was updated with the latest developments in the field.

  • New sections include recent X-ray detector technology; photon counting CT; dynamic (cardiac, perfusion) CT; multi-energy CT; parallel MR imaging; phase-based (susceptibility weighted, chemical shift) MRI; arterial spin labeled perfusion MRI; magnetic particle imaging; functional CT, MRI and ultrasound imaging; time-of-flight PET; hybrid imaging (PET-CT, SPECT-CT, PET-MRI); speckle tracking echography and tissue deformation mapping; acoustic shear waves and elasticity imaging; harmonic ultrasound imaging; and transducers for 3D ultrasound imaging.
  • Needless to say that the sections on current equipment, their clinical use and biological impact, and the expected developments in the domain are up-to-date in this edition.
  • The whole chapter on medical image analysis was totally revised and a new section on pattern recognition was added.
  • The list of exercises for self-assessment has doubled.
  • As compared to the previous edition, the large majority of images was renewed and many of them were augmented with video clips.
  • Finally, many minor changes resulted from suggestions and comments from researchers, clinicians and students.